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Close gaps in culture-based testing before they delay product release
Culture-based mycoplasma methods can extend timelines and may not detect every relevant organism fast enough for today’s cell therapy workflows. This application note reviews data from a qPCR-based ... read more
rAAV production using HEK293 cell line and modified transfection medium
As the race to deliver advanced gene therapies accelerates, AAV production must keep pace—with no room for inconsistency. This article dives into how high-performance cell culture media is unlocking ... read more
Adherent vs suspension cell culture: it’s your choice
Choosing between adherent cell culture and suspension cell culture is not always an obvious choice. Each production method can offer specific advantages to gene therapy manufacturing. However, as ... read more
Monitoring to manufacturing: Cyto-Facto’s approach to safe and scalable cell and gene therapies
Discover how Cyto-Facto and Dr. Shin Kawamata and his team are overcoming the unique challenges of living therapies — such as maintaining sterility, standardization and traceability — by integrating ... read more
A novel transient cell line to enable high yield and scalable rAAV production with low encapsidated host cell DNA
Obtain efficient and scalable production of rAAVs by transient transfection across multiple serotypes with low levels of encapsidated hcDNA. read more

[eBook] The science of transformation: Exploring CAR-T, iPSC differentiation, and gene delivery
Gain insights into challenges and solutions in CAR-T discovery and development, optimizing human hepatic organoid development, high-throughput screening and characterization of LNP formulations for ... read more
[eBook] Mastering advanced cell cultures with superior media and live-cell insights
The right cell culture formulation is key for the success of cell-based experiments and applications. It impacts everything from the basic health of the cells to the integrity and applicability of the... read more
[eBook] Expediting cell and gene therapy development
This eBook covers recent advances that have accelerated investment and driven an increasing number of trials and approvals of advanced therapies. read more

Connecting for quality: Powering cGMP for cell and gene therapies
In this infographic, review the most common cGMP hurdles faced in the CGT industry, and the automation and digital solutions that are helping the industry move forward. read more
The global compliance puzzle: CGT regulatory considerations
In this infographic, explore common global regulatory hurdles, and the digital solutions that can complete the global compliance puzzle. read more
[Infographic] Strategies for overcoming challenges in cell and gene therapy manufacturing
The production of cell and gene therapies comes with a set of challenges, including scalability, compliance, and accuracy. Manufacturing execution systems (MES) that incorporate digital process ... read more

[Interview] Engineering the future of neuromuscular gene therapy
Karen Langhauser is joined by Kasturi Sengupta, Ph.D., to discuss how AAV vector design, serotype selection, and delivery strategies are shaping the future of neuromuscular gene therapy.
Cracking the code: Why cell line development matters for AAV therapies
Discover how cutting-edge cell line innovations are transforming AAV manufacturing.
Small scale, big impact: LevMixer™ 10 L single-use mixing system
Introducing the LevMixer™ 10 L mixer: a benchtop, single-use mixing system for 100 mL to 10 L volumes. Designed for GxP environments, it features integrated temperature, pH, and weight sensing, low ...

Applied Biosystems™ SteriSEQ™ Rapid Sterility Testing Kit
The Applied Biosystems™ SteriSEQ™ Rapid Sterility Testing Kit is a TaqMan™ based qPCR solution for rapid detection of bacterial and fungal contamination in complex bioproduction samples. Designed for cell therapy manufacturing workflows, it delivers ... read more
Dual AAV-GFP Controls
Dual AAV-GFP controls include two AAV vectors, each carrying half of the GFP reporter. When co-delivered, homologous recombination restores the full-length mRNA, producing functional GFP. These controls provide a fast, visual proof-of-concept to ... read more
ProteanFect™ TuffCell Transfection Kit
A non-viral, non-liposomal, coacervate-based nucleic acid delivery platform based on mammalian endogenous protein, offering novel solution for efficient gene delivery. Features ProteanFect is a protein-based, non-viral transfection reagent ... read more