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Scaling up for success: Master tips for CGT process design and regulatory preparation
Tuesday, July 29, 2025
Scaling up cell and gene therapy processes requires more than just technical expertise; it demands early planning, smart design, and a deep understanding of regulatory expectations. This article explores key considerations for moving from ...
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Molecular approaches to streamline cell therapy product analytical testing
Tuesday, July 29, 2025
Cutting-edge molecular tools are transforming the way cell therapy products are analyzed, offering faster, more sensitive, and less invasive testing methods compared to traditional approaches. This article explores how techniques like qPCR,...
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Literature review of applications and processes in iCELLis™ bioreactor
Friday, June 06, 2025
As of 2023, six therapeutic drugs manufactured in the iCELLis™ bioreactor were approved, and that number is expected to rise. Gain an overview of how scientists have used the iCELLis™ bioreactor family in a variety of applications.
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Scale-up of an ELEVECTA™ transient rAAV production process in the Xcellerex™ X-platform single-use bioreactor
Friday, June 06, 2025
Are you looking to achieve scalable, high-titer manufacturing of high-quality rAAV products? Achieve your goal with the next-generation Xcellerex™ X-platform single-use bioreactor used in tandem with the ELEVECTA™ transient cell line and ...
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Adherent vs suspension cell culture: it’s your choice
Friday, June 06, 2025
Choosing between adherent cell culture and suspension cell culture is not always an obvious choice. Each production method can offer specific advantages to gene therapy manufacturing. However, as there are so many different considerations ...
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Mitigating adventitious agent risks in CGT: Innovations in detection and control
Wednesday, May 14, 2025
As the cell and gene therapy (CGT) industry rapidly expands, maintaining product safety and quality is more critical than ever. One of the most pressing concerns is the threat of adventitious agents—unintended microbial contaminants that ...
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Scaling up for success: What sets cell and gene therapy developers apart early on
Thursday, May 08, 2025
As the cell and gene therapy industry rapidly expands, developers face mounting pressure to scale efficiently while navigating complex regulatory and manufacturing landscapes. This article explores the strategies top innovators use to ...
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ELEVECTA™ cell lines | Make AAV your way
Friday, April 18, 2025
Combining innovative design and deep expertise, the transient, packaging, and stable producer cell lines, based on HEK293, provide competitive performance, high quality, and flexibility for your AAV production.
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Facts about AAV producer cell lines
Thursday, April 17, 2025
Explore the development and benefits of adeno-associated virus (AAV) producer cell lines, including their role in simplifying AAV production, enhancing scalability, and ensuring consistent quality in gene therapy applications.
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A novel transient cell line to enable high yield and scalable rAAV production with low encapsidated host cell DNA
Thursday, April 17, 2025
Obtain efficient and scalable production of rAAVs by transient transfection across multiple serotypes with low levels of encapsidated hcDNA.
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Cell therapy system provides one-step isolation and activation with flexible active release to optimize T cell phenotype
Friday, November 01, 2024
Antibody-coated magnetic beads were crucial in the manufacturing process to achieve one-step cell isolation and activation, and enabled clinical-scale dose production within 2 to 3 weeks. Since then, the technology has become well ...
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Navigating the complex testing strategies for viral vector-based gene therapies
Friday, November 01, 2024
Safely introducing transgenes into cells is one of the greatest challenges facing the field of gene therapy. Using viral vectors has become one of the most effective means to achieve this by taking advantage of a virus’s natural ability to ...
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