Unlocking Primary Cell Transfection

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ProteanFect™ TuffCell Transfection Kit is a novel, protein-based system designed to deliver nucleic acids efficiently and safely into difficult-to-transfect cell types. Using a coacervate-based mechanism derived from engineered mammalian proteins, ProteanFect provides a non-viral, non-liposomal, and non-electroporation alternative for nucleic acid delivery. The reagent achieves high transfection efficiency while maintaining low cytotoxicity, making it particularly suitable for sensitive primary cells and complex cell lines such as immune cells, stem cells, and neurons. This system enables reliable gene expression, silencing, and editing applications where conventional methods often perform poorly.

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