Cell therapy system provides one-step isolation and activation with flexible active release to optimize T cell phenotype

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Antibody-coated magnetic beads were crucial in the manufacturing process to achieve one-step cell isolation and activation, and enabled clinical-scale dose production within 2 to 3 weeks. Since then, the technology has become well established in the industry and has been used in over 200 clinical trials to provide critically needed treatment for patients. Despite these successes, challenges remain to further improve the reliability, consistency, and longevity of treatment outcomes. As well, there is still a need to accelerate and expand treatment delivery to patients. Download this application note to learn more how cell therapy system (CTS) Detachable Dynabeads CD3/CD28 were used to achieve one-step isolation and activation with flexible active release to optimize T cell phenotype.

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