Description
Dual AAV-GFP controls include two AAV vectors, each carrying half of the GFP reporter. When co-delivered, homologous recombination restores the full-length mRNA, producing functional GFP. These controls provide a fast, visual proof-of-concept to validate dual-AAV co-delivery and recombination efficiency before moving to custom Dual AAV constructs.
Benefits:
- Overcome the Packaging Limit – Dual AAV vectors bypass the ~4.7 kb cargo restriction, enabling efficient delivery of large genes.
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Enable Complex Applications – Expand your experimental scope by studying multi-component or oversized genetic constructs that cannot be packaged into a single AAV vector.